chi chi pup Posted January 4, 2012 Report Share Posted January 4, 2012 Hi, I posted awhile ago about Cheyenne testing positive for Lyme disease, we started her on doxy and 1 month later checked her blood and her ALT has shot up to 900. She previously had an ALT# at 300 due to gall bladder sludge which we found on an ultrasound, her liver was perfect. We started her on Ursidol and the reading came down to normal range. Now one month of doxy and this 900 reading, vet said it probably because of the doxy, to stop and re-check her blood next week. Has anyone heard of the ALT shooting that high after being on doxy? And if it is the doxy what other antibiotic is used to treat Lyme? Thank-you, Cindi Link to comment Share on other sites More sharing options...
gcv-border Posted January 4, 2012 Report Share Posted January 4, 2012 ..... And if it is the doxy what other antibiotic is used to treat Lyme? Thank-you, Cindi My vet will use amoxicillin for dogs whose digestive system gets too upset on doxy. Jovi Link to comment Share on other sites More sharing options...
juliepoudrier Posted January 4, 2012 Report Share Posted January 4, 2012 Amoxicillin is the substitute of choice. It is cleared through the kidneys, so shouldn't add to the liver issue. If I were you, I'd consider putting Cheyenne on milk thistle to help her liver. There is a product that the folks on Tick-L recommend, Country Life Liver Support Factor, which is made by Biochem. A Google search will find it. I give this daily to my epileptic dog who is on phenobarbital and also have used it in the past when treating any dog with doxy. Milk thistle is probably easier (quicker) to come by, but do get one or the other and start giving it to Cheyenne. J. Link to comment Share on other sites More sharing options...
chi chi pup Posted January 5, 2012 Author Report Share Posted January 5, 2012 Amoxicillin is the substitute of choice. It is cleared through the kidneys, so shouldn't add to the liver issue. If I were you, I'd consider putting Cheyenne on milk thistle to help her liver. There is a product that the folks on Tick-L recommend, Country Life Liver Support Factor, which is made by Biochem. A Google search will find it. I give this daily to my epileptic dog who is on phenobarbital and also have used it in the past when treating any dog with doxy. Milk thistle is probably easier (quicker) to come by, but do get one or the other and start giving it to Cheyenne. J. Link to comment Share on other sites More sharing options...
chi chi pup Posted January 5, 2012 Author Report Share Posted January 5, 2012 Hi, Cheyenne is on S-Adenosyl-425 for liver support and thank-you Julie I did join the tick-l. I will check out the Country Life Liver Support. Cindi Link to comment Share on other sites More sharing options...
BCjetta Posted January 7, 2012 Report Share Posted January 7, 2012 My dog had issues with a high ALT in the past as well. I think initially it was less than 100 but after going on pred it increased to over 500. The vet I work with wasn't concerned as that can be a normal side effect. Once she was off the pred, the level went back down to normal. Are any of the other liver enzymes elevated? Link to comment Share on other sites More sharing options...
chi chi pup Posted January 8, 2012 Author Report Share Posted January 8, 2012 Her AST was 90, this is the first time this has ever been elevated so I'm thinking it is the doxy. She is going for a blood test this Tues. and I am going to fast her this time to see if that makes a difference. Cindi Link to comment Share on other sites More sharing options...
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