Report Doxy and stomachs in General Border Collie Discussion Posted May 17, 2010 doxy can affect their appetites, especially at the doses recommended to treat TBD. I currently have a dog on doxy and his appetite is improved.....one of the suggestions I read here: http://sites.google.com/site/blackgsd/ canine tick borne disease information page, suggested giving the dog probiotics a couple of hours after every dose of doxy, theory being you are killing good bugs(stomach flora) along with the bad bugs. I am not doing it after every dose, what I did was go to TSC and get a lg tube of Probios over in the horse section, it is just a gel with all the good bugs concentrated in it. So in the mornings, 3 or 4 hours after the morning round of doxy I squeeze out about 1 inch or a little less of the gel and place it on the back of his tongue, he will actually eat it on a dog biscuit. That is working well for my dog, maybe it will help your dog too. TBDs suck.